Receptor Binding Assay for Paralytic Shellfish Poisoning Toxins: Optimization and Interlaboratory Comparison
نویسندگان
چکیده
منابع مشابه
Immunoassay methods for paralytic shellfish poisoning toxins.
The current status of immunochemical techniques for analysis of paralytic shellfish poisoning (PSP) toxins is summarized. Important aspects regarding production of the biological reagents necessary for immunochemical methods, the characteristics of polyclonal and monoclonal antibodies against saxitoxin and neosaxitoxin, and the importance of test sensitivity and specificity are discussed. Appli...
متن کاملParalytic Shellfish Poisoning Toxins: Biochemistry and Origin
Plankton feeders such as bivalves often become toxic. Human consumption of the toxic bivalve causes severe food poisoning, including paralytic shellfish poisoning (PSP) which is the most dangerous because of the acuteness of the symptoms, high fatality and wide distribution throughout the world. Accumulation of PSP toxins in shellfish has posed serious problems to public health and fisheries in...
متن کاملDevelopment of reference materials for paralytic shellfish poisoning toxins.
A project was undertaken to develop mussel reference materials that were certified for their mass fractions of saxitoxin and decarbamoyl-saxitoxin. Fifteen laboratories from various European countries participated. Three of these had major responsibility for substantial parts of the work and overall coordination of the project. The project involved 4 main activities: (1) procurement and charact...
متن کاملComparison of analytical tools and biological assays for detection of paralytic shellfish poisoning toxins.
The paralytic shellfish poisoning toxins (PSTs) were, as their name suggests, discovered as a result of human poisoning after consumption of contaminated shellfish. More recently, however, the same toxins have been found to be produced by freshwater cyanobacteria. These organisms have worldwide distribution and are common in our sources of drinking water, thus presenting another route of potent...
متن کاملShellfish Poisoning and Toxins
Shellfish toxins are the most dangerous marine biotoxins, and produced by free living micro-algae. Shellfish toxins are concentrated in flesh, and poisoning occurs when these contaminated shellfish is consumed. They can cause paralytic shellfish poisoning (PSP), diarrhetic shellfish poisoning (DSP), neurotoxic shellfish poisoning (NSP), amnesic shellfish poisoning (ASP) and azaspiracid shellfis...
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ژورنال
عنوان ژورنال: Journal of AOAC INTERNATIONAL
سال: 2003
ISSN: 1060-3271,1944-7922
DOI: 10.1093/jaoac/86.4.737